Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | BCR | P11274 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28767599 | 0.98 | METAP2 (0.51) | METAP2ABL1ABCB1BCRPARP1 | |
| SCHEMBL27729410 | 0.84 | ESR2 (0.46) | METAP2PARP1CCR1RAB9ACCR5 | |
| SCHEMBL2115749 | 0.81 | CCR1 (0.64) | METAP2PARP1CCR1RAB9ACCR5 | |
| SCHEMBL27594921 | 0.80 | METAP2 (0.53) | METAP2PARP1TGFBR1CCR1RAB9A | |
| 8-Hydroxy Quinaldine SCHEMBL195825 | 0.78 | METAP2 (0.72) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL27650187 | 0.78 | METAP2 (0.72) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL132450 | 0.77 | METAP2 (0.70) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL461474 | 0.77 | METAP2 (0.70) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL5142152 | 0.77 | METAP2 (0.70) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL21141877 | 0.77 | METAP2 (0.70) | METAP2PARP1CCR1RAB9ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492424-A | Indenoindole derivative and organic electroluminescent element | HODOGAYA CHEMICAL CO LTD | 2016-04-13 | — | — | CN | disclosed |
| CN-105452255-A | Dicarbazole derivative and organic electroluminescent element | HODOGAYA CHEMICAL CO LTD | 2016-03-30 | — | — | CN | disclosed |
| CN-105143198-A | Novel naphthotriazole derivative and organic electroluminescence element | HODOGAYA CHEMICAL CO LTD | 2015-12-09 | — | — | CN | disclosed |