Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037982 | 0.98 | METAP2 (0.53) | METAP2ABL1ABCB1BCRPARP1 | |
| SCHEMBL27729410 | 0.86 | ESR2 (0.46) | METAP2PARP1CCR1RAB9ACCR5 | |
| SCHEMBL2115749 | 0.80 | CCR1 (0.64) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL21141877 | 0.79 | METAP2 (0.70) | METAP2PARP1CCR1RAB9ACCR5 | |
| SCHEMBL27594921 | 0.79 | METAP2 (0.53) | METAP2PARP1TGFBR1CCR1RAB9A | |
| 8-Hydroxy Quinaldine SCHEMBL28331020 | 0.78 | METAP2 (0.68) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL28119347 | 0.78 | METAP2 (0.68) | METAP2PARP1CCR1RAB9ACCR5 | |
| SCHEMBL27608317 | 0.77 | METAP2 (0.50) | METAP2PARP1MAPTGAAALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL27650187 | 0.77 | METAP2 (0.72) | METAP2PARP1CCR1RAB9ACCR5 | |
| 8-Hydroxy Quinaldine SCHEMBL195825 | 0.77 | METAP2 (0.72) | METAP2PARP1CCR1RAB9ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546034-C | Semiconductor device and manufacture method thereof | SEMICONDUCTOR ENERGY LAB (JP) | 2009-09-30 | — | — | CN | disclosed |
| CN-101124677-A | Semiconductor device and preparing method thereof | SEMICONDUCTOR ENERGY LAB (JP) | 2008-02-13 | — | — | CN | disclosed |