SCHEMBL28038015

SCHEMBL28038015

C=C(C)C(=O)OCCc1cccc2nc3ccccc3cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
POLB P06746 3/20 0.38
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.38
GLA P06280 2/20 0.38
GAA P10253 2/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
PTBP1 P26599 1/20 0.38
RAB9A P51151 1/20 0.38
RCE1 Q9Y256 1/20 0.38
CDYL Q9Y232 1/20 0.38
MTNR1A P48039 7/20 0.37
MTNR1B P49286 7/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
TLR8 Q9NR97 1/20 0.37
MEN1 O00255 2/20 0.36
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68440 0.83 CDYL (0.49) KDM4EALDH1A1KMT2ACDYLMTNR1A
SCHEMBL31467476 0.83 CDYL (0.49) KDM4EALDH1A1KMT2ACDYLMTNR1A
Hydrochloric Acid SCHEMBL31467475 0.81 CDYL (0.47) KDM4EALDH1A1KMT2ACDYLMTNR1A
SCHEMBL29503685 0.78 MTNR1A (0.44) POLBMTNR1AMTNR1BAPEX1HTT
SCHEMBL29503732 0.77 MTNR1A (0.46) POLBMTNR1AMTNR1BAPEX1HTT
SCHEMBL28989935 0.76 POLB (0.47) POLBMTNR1AMTNR1BAPEX1HTT
SCHEMBL13609812 0.76 MEN1 (0.43) KDM4EPOLBALDH1A1KMT2AGLA
SCHEMBL23421423 0.75 KMT2A (0.58) KDM4EPOLBALDH1A1KMT2AGLA
SCHEMBL29631756 0.75 KMT2A (0.58) KDM4EPOLBALDH1A1KMT2AGLA
SCHEMBL11963930 0.74 HTT (0.42) KDM4EPOLBCHRM5CHRM1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111533668-A Cyanostilbenes 罗利克技术有限公司 2020-08-14 CN disclosed
CN-107000416-A Polyolefin film 埃克森美孚化学专利公司 2017-08-01 CN disclosed
CN-105377811-A Cyanostilbenes ROLIC AG 2016-03-02 CN disclosed