Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072099 | 0.76 | CHRNB2 (0.44) | KDM4EALDH1A1HPGDPKMALOX12 | |
| SCHEMBL811572 | 0.74 | SLC6A2 (0.42) | KDM4EALDH1A1HPGDPKMALOX12 | |
| SCHEMBL27940801 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1HPGDPKMALOX12 | |
| SCHEMBL2855095 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1HPGDPKMALOX12 | |
| SCHEMBL5585868 | 0.69 | POLB (0.41) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL27815721 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1HPGDPKMALOX12 | |
| SCHEMBL28233675 | 0.69 | SLC6A2 (0.44) | HPGDSLC18A3SIGMAR1KMT2ASMN1; SMN2 | |
| SCHEMBL8967839 | 0.69 | CHRNB4 (0.50) | KDM4EALDH1A1HPGDPKMALOX12 | |
| SCHEMBL3821337 | 0.68 | HTR2C (0.40) | KDM4EALDH1A1HPGDPKMALOX12 | |
| SCHEMBL4587533 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1HPGDPKMALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011343-A | Novel pyrazole derivative | 持田制药株式会社 | 2017-08-04 | — | — | CN | claimed |
| CN-105189493-B | Novel Pyrazole Derivatives | 持田制药株式会社 | 2017-04-12 | — | — | CN | claimed |
| CN-107011343-A | Novel pyrazole derivative | 持田制药株式会社 | 2017-08-04 | — | — | CN | disclosed |
| CN-106957317-A | Novel pyrazole derivative | 持田制药株式会社 | 2017-07-18 | — | — | CN | disclosed |
| CN-105189493-B | Novel Pyrazole Derivatives | 持田制药株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-105189493-A | Novel Pyrazole Derivatives | MOCHIDA PHARM CO LTD | 2015-12-23 | — | — | CN | disclosed |