SCHEMBL2855095

SCHEMBL2855095

C=CN1CCNC1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.35
PKM P14618 1/20 0.35
ALOX12 P18054 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RECQL P46063 1/20 0.33
SLC18A3 Q16572 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PRCP P42785 3/20 0.33
SLC6A2 P23975 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
SLC6A3 Q01959 1/20 0.32
GAA P10253 1/20 0.32
CYP2C19 P33261 1/20 0.30
CHRNB2 P17787 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28038145 0.72 KDM4E (0.43) KDM4EALDH1A1HPGDPKMALOX12
SCHEMBL7072099 0.72 CHRNB2 (0.44) KDM4EALDH1A1HPGDPKMALOX12
SCHEMBL27662499 0.71 POLB (0.39) SIGMAR1PRCPSLC6A2SLC6A3CYP2C19
SCHEMBL811572 0.70 SLC6A2 (0.42) KDM4EALDH1A1HPGDPKMALOX12
SCHEMBL27940801 0.68 KDM4E (0.44) KDM4EALDH1A1HPGDPKMALOX12
Benzaldehyde SCHEMBL27516622 0.66 ALDH1A1 (0.42) KDM4EALDH1A1HPGDPKMALOX12
SCHEMBL27815721 0.66 KDM4E (0.39) KDM4EALDH1A1HPGDPKMALOX12
SCHEMBL5585868 0.66 POLB (0.41) KDM4EALDH1A1KMT2A
SCHEMBL18927526 0.66 CHRNB2 (0.55) RECQLCHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL8967839 0.66 CHRNB4 (0.50) KDM4EALDH1A1HPGDPKMALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761587-B1 PLASTISOLS BASED ON A METHYLMETHACRYLATE COPOLYMER EVONIK ROEHM GMBH (DE) 2010-01-20 EP claimed
US-20230124643-A1 ELASTIC MATERIALS PREPARED FROM ENERGY-CURABLE LIQUID COMPOSITIONS ARKEMA FRANCE (FR) 2023-04-20 US disclosed
EP-4127004-A1 ELASTIC MATERIALS PREPARED FROM ENERGY-CURABLE LIQUID COMPOSITIONS ARKEMA FRANCE (FR) 2023-02-08 EP disclosed
WO-2021198398-A1 ELASTIC MATERIALS PREPARED FROM ENERGY-CURABLE LIQUID COMPOSITIONS ARKEMA FRANCE (FR) 2021-10-07 WO disclosed
CN-102417560-B The pigment efficiency of multistage emulsion polymer and improvement Rohm and Haas Co. (US) Independence Mall West, Philadelphia, Pennsylvania. U.S.A (US) 2015-11-25 CN disclosed
CN-102417776-B Stable aqueous composite compositions ROHM & HAAS 2015-02-25 CN disclosed
CN-102417560-A Multistage emulsion polymer and improved pigment efficiency ROHM & HAAS 2012-04-18 CN disclosed
CN-102417776-A Stable aqueous composite compositions ROHM & HAAS 2012-04-18 CN disclosed
CN-1847320-B Aqueous polymer dispersions ROHM & HAAS 2010-06-23 CN disclosed
CN-100509979-C Polymer composition and monomeric composition preparied using the same ROHM & HAAS (US) 2009-07-08 CN disclosed
CN-1576334-A Aqueous polymer composition ROHM & HAAS (US) 2005-02-09 CN disclosed
CN-1536045-A Normal temp. solidified polymer 罗姆和哈斯公司 2004-10-13 CN disclosed
CN-1502665-A Aqueous coating composition 罗姆和哈斯公司 2004-06-09 CN disclosed
CN-1450114-A Aqueous polymer blend composition ROHM & HAAS (US) 2003-10-22 CN disclosed
CN-1443819-A Polymer composition and monomeric composition preparied using the same ROHM & HAAS (US) 2003-09-24 CN disclosed
US-6566441-B1 Storage stability; compatibility with low-cost plasticisers; permit a relatively high binder content ROEHM GMBH & CO KG (DE) 2003-05-20 US disclosed
CN-1407044-A Improved coating and coating composition ROHM & HAAS (US) 2003-04-02 CN disclosed
CN-1371949-A Improved coating method ROHM & HAAS (US) 2002-10-02 CN disclosed
EP-0407800-A2 Analysis method for determining substances from biological fluids MILES INC. (US) 1991-01-16 EP disclosed
EP-0220603-B1 PROCESS FOR PREPARING POWDERY POLYMERS BASF Aktiengesellschaft (DE) 1989-09-13 EP disclosed