Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42349 | 0.98 | — | — | |
| SCHEMBL17539134 | 0.83 | ALOX5AP (0.42) | CHEK1CA12CA1CA2CA4 | |
| SCHEMBL17502178 | 0.81 | ALDH1A1 (0.50) | CHEK1KDM4EMEN1KMT2AEGLN2 | |
| SCHEMBL30859509 | 0.80 | P4HTM (0.44) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3413808 | 0.78 | ALDH1A1 (0.52) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL17539185 | 0.77 | CYP3A4 (0.50) | CHEK1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17539186 | 0.77 | CHEK1 (0.53) | CHEK1ALDH1A1L3MBTL1EGFRAR | |
| SCHEMBL18419348 | 0.74 | — | — | |
| SCHEMBL22495364 | 0.73 | MAPT (0.47) | CHEK1ADRA2CKDM4EMEN1KMT2A | |
| SCHEMBL7085448 | 0.73 | PDE10A (0.42) | CHEK1KDM4EMEN1KMT2AEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175453-B | A kind of manganese complex is prepared and its synthetic method | 合肥工业大学 | 2017-09-26 | — | — | CN | disclosed |
| CN-105175453-A | Manganese complex preparation and synthesis method | UNIV HEFEI TECHNOLOGY | 2015-12-23 | — | — | CN | disclosed |