⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038567 | 0.98 | CHEK1 (0.38) | — | |
| SCHEMBL17539134 | 0.85 | ALOX5AP (0.42) | — | |
| SCHEMBL17502178 | 0.83 | ALDH1A1 (0.50) | — | |
| SCHEMBL30859509 | 0.82 | P4HTM (0.44) | — | |
| SCHEMBL3413808 | 0.80 | ALDH1A1 (0.52) | — | |
| SCHEMBL17539186 | 0.78 | CHEK1 (0.53) | — | |
| SCHEMBL17539185 | 0.78 | CYP3A4 (0.50) | — | |
| SCHEMBL18419348 | 0.76 | — | — | |
| SCHEMBL7085448 | 0.74 | PDE10A (0.42) | — | |
| SCHEMBL7642979 | 0.74 | PDE10A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028642-B | Diaryl dihydrofuro [3,4-d ] pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2024-07-12 | — | — | CN | claimed |
| CN-108976325-B | Amidoxime pyridine chelate resin and preparation method thereof | 海南师范大学 | 2020-07-31 | — | — | CN | claimed |
| CN-108976325-A | A kind of amidoxime group pyridine chelating resin and preparation method thereof | 海南师范大学 | 2018-12-11 | — | — | CN | claimed |
| CN-105175453-B | A kind of manganese complex is prepared and its synthetic method | 合肥工业大学 | 2017-09-26 | — | — | CN | claimed |
| CN-105669710-B | A kind of preparation of copper complex crystal and its synthetic method | 合肥祥晨化工有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-105669772-A | Preparation and synthesis method of nickel complex | 合肥祥晨化工有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-105669710-A | Preparation method and synthetic method for copper complex crystal | 合肥祥晨化工有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-105175453-A | Manganese complex preparation and synthesis method | UNIV HEFEI TECHNOLOGY | 2015-12-23 | — | — | CN | claimed |
| EP-2507243-B1 | SPIROINDOLINONE PYRROLIDINES | HOFFMANN LA ROCHE (CH) | 2015-06-10 | — | — | EP | claimed |
| EP-2507243-A1 | SPIROINDOLINONE PYRROLIDINES | F. Hoffmann-La Roche AG (CH) | 2012-10-10 | — | — | EP | claimed |
| JP-2006500348-A | — | — | 2006-01-05 | — | — | JP | claimed |
| US-20050197349-A1 | Pyrrolo[2,3-D]pyrimidine compounds | PFIZER INC. | 2005-09-08 | — | — | US | claimed |
| WO-2005066155-A1 | 5-FLUORO-, CHLORO- AND CYANO-PYRIDIN-2-YL-TETRAZOLES AS LIGANDS OF THE METABOTROPIC GLUTAMATE RECEPTOR-5 | ASTRAZENECA AB (SE) | 2005-07-21 | — | — | WO | claimed |
| EP-1534685-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | Astex Technology Limited (GB) | 2005-06-01 | — | — | EP | claimed |
| US-6696567-B2 | INHIBITION OF PROTEIN KINASES OR JANUS KINASE 3; TREATING OR PREVENTING ORGAN TRANSPLANT REJECTION, XENO TRANSPLATION, LUPUS, MULTIPLE SCLEROSIS, RHEUMATOID ARTHRITIS, PSORIASIS, TYPE I DIABETES OR VARIOUS DISEASE COMPLICATIONS | PFIZER INC. | 2004-02-24 | — | — | US | claimed |
| WO-2004014864-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | ASTEX TECHNOLOGY LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
| US-20030220353-A1 | Pyrrolo[2,3-d]pyrimidine compounds | PFIZER INC. | 2003-11-27 | — | — | US | claimed |
| EP-1294724-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS AS IMMUNOSUPPRESSIVE AGENTS | Pfizer Products Inc. (US) | 2003-03-26 | — | — | EP | claimed |
| US-20020068746-A1 | Pyrrolo[2,3-d]pyrimidine compounds | PFIZER INC. | 2002-06-06 | — | — | US | claimed |
| WO-2002000661-A1 | PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS AS IMMUNOSUPPRESSIVE AGENTS | PFIZER PRODUCTS INC. (US) | 2002-01-03 | — | — | WO | claimed |