Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022567 | 0.89 | ADORA2A (0.68) | ADORA2AADORA1MAPTLMNACYP19A1 | |
| SCHEMBL6038198 | 0.87 | ADORA2A (0.46) | ADORA2AADORA1MAPTLMNACYP19A1 | |
| SCHEMBL10942195 | 0.86 | ABCG2 (0.47) | ADORA2AADORA1MAPTLMNAMEN1 | |
| SCHEMBL5672174 | 0.86 | HTT (0.46) | ADORA2AADORA1MAPTLMNACYP19A1 | |
| SCHEMBL19054160 | 0.82 | ADORA2A (0.82) | ADORA2AADORA1MAPTLMNASMN1; SMN2 | |
| SCHEMBL980050 | 0.79 | MAPT (0.62) | MAPTLMNACYP19A1SMN1; SMN2MEN1 | |
| SCHEMBL10940853 | 0.78 | NOS2 (0.49) | ADORA2AADORA1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3720836 | 0.78 | ADORA2A (0.79) | ADORA2AADORA1MAPTLMNAMEN1 | |
| SCHEMBL8490725 | 0.78 | ADORA2A (0.56) | ADORA2AADORA1MAPTLMNACYP19A1 | |
| SCHEMBL9791640 | 0.78 | ADORA2A (0.62) | ADORA2AADORA1MAPTLMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164116-A | Heteroaryl substituted indazoles | Bayer Pharma AG | 2015-12-16 | — | — | CN | claimed |
| CN-105051030-A | Diaminoheteroaryl substituted indazoles | Bayer Pharma AG | 2015-11-11 | — | — | CN | claimed |
| CN-105164116-A | Heteroaryl substituted indazoles | Bayer Pharma AG | 2015-12-16 | — | — | CN | disclosed |
| CN-105051030-A | Diaminoheteroaryl substituted indazoles | Bayer Pharma AG | 2015-11-11 | — | — | CN | disclosed |