Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27417453 | 0.86 | HTR2A (0.45) | HTR2AHTR2CACLYCDK4CCND1 | |
| SCHEMBL29703068 | 0.85 | HTR2A (0.50) | HTR2AHTR2CACLYCDK4CCND1 | |
| Ethoxycarbonyl Group SCHEMBL27449974 | 0.84 | HTR2A (0.47) | HTR2AHTR2CACLYCDK4CCND1 | |
| Ethoxycarbonyl Group SCHEMBL27418243 | 0.81 | HTR2A (0.49) | HTR2AHTR2CCDK4CCND1KRAS | |
| Ethoxycarbonyl Group SCHEMBL28746661 | 0.76 | HTR2A (0.44) | HTR2AHTR2CACLYCDK4CCND1 | |
| SCHEMBL27682298 | 0.76 | HTR2A (0.48) | HTR2AHTR2CACLYCDK4CCND1 | |
| Ethoxycarbonyl Group SCHEMBL27450453 | 0.74 | SLC6A2 (0.44) | HTR2AHTR2CKRASPLGPLAU | |
| SCHEMBL18856947 | 0.74 | HTR2A (0.55) | HTR2AHTR2CACLYCDK4CCND1 | |
| SCHEMBL18856955 | 0.73 | HTR2A (0.56) | HTR2AHTR2CACLYCDK4CCND1 | |
| Ethoxycarbonyl Group SCHEMBL28823657 | 0.71 | HTR6 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392787-A | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-09 | — | — | CN | disclosed |