Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27814870 | 0.90 | HTR6 (0.53) | HTR6POLBL3MBTL1HDAC1PPARG | |
| Ethoxycarbonyl Group SCHEMBL27701550 | 0.86 | HTR6 (0.68) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL428128 | 0.85 | HTR6 (0.68) | HTR6POLBL3MBTL1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL27682289 | 0.79 | HTR6 (0.47) | HTR6MEN1KMT2ALMNA | |
| SCHEMBL27733772 | 0.79 | HTR6 (0.51) | HTR6POLBL3MBTL1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL28073916 | 0.78 | HTR6 (0.56) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL19181960 | 0.75 | HTR6 (0.47) | HTR6POLBL3MBTL1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL27580233 | 0.75 | MEN1 (0.58) | HTR6POLBL3MBTL1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL27418243 | 0.75 | HTR2A (0.49) | POLB | |
| SCHEMBL4446722 | 0.75 | HTR6 (0.59) | HTR6POLBL3MBTL1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431419-A | Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN-LA ROCHE AG | 2016-03-23 | — | — | CN | disclosed |
| CN-105408330-A | Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-16 | — | — | CN | disclosed |