Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288898 | 1.00 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL924219 | 1.00 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL8562595 | 1.00 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL29463686 | 1.00 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL28114454 | 0.98 | GAA (0.53) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| Tert-Butylamine SCHEMBL28768909 | 0.91 | EPHX2 (0.51) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL8901298 | 0.85 | GAA (0.47) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL6419360 | 0.84 | MTNR1A (0.49) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL31181154 | 0.84 | MTNR1A (0.49) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL8562039 | 0.84 | MTNR1A (0.56) | GAAMAPTMTNR1AMTNR1BEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111254181-B | Method for preparing (S) -1,2,3, 4-tetrahydroisoquinoline-3-formic acid by chemical enzyme method | 苏州同力生物医药有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-111254170-B | Method for preparing (S) -1,2,3, 4-tetrahydroisoquinoline-3-formic acid by multienzyme coupling | 浙江大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-111254180-B | Method for preparing (S) -1,2,3, 4-tetrahydroisoquinoline-3-formic acid by enzymatic resolution | 浙江大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-111254180-A | Method for preparing (S) -1,2,3, 4-tetrahydroisoquinoline-3-formic acid by enzymatic resolution | 浙江大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-111254170-A | Method for preparing (S) -1,2,3, 4-tetrahydroisoquinoline-3-formic acid by multi-enzyme coupling | 浙江大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-111254181-A | Method for preparing (S) -1,2,3, 4-tetrahydroisoquinoline-3-formic acid by chemoenzymatic method | 苏州同力生物医药有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-104945345-A | Chiral morpholine compounds and preparation method thereof as well as chiral amino acid compounds and preparation method and application thereof | SHENZHEN NEPTUNUS INTERLONG BIO TECH CO LTD | 2015-09-30 | — | — | CN | disclosed |