Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562595 | 0.85 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL924219 | 0.85 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL30288898 | 0.85 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL28038780 | 0.85 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL29463686 | 0.85 | GAA (0.54) | GAAMAPTMTNR1AMTNR1BEPHX2 | |
| SCHEMBL28114454 | 0.84 | GAA (0.53) | GAAMAPTMTNR1AMTNR1BMAPK1 | |
| SCHEMBL10474535 | 0.83 | MAPT (0.51) | GAAMAPTMTNR1AMTNR1BMAPK1 | |
| Tert-Butylamine SCHEMBL28768909 | 0.78 | EPHX2 (0.51) | GAAMAPTMTNR1AMTNR1BMAPK1 | |
| Bromide SCHEMBL23699446 | 0.74 | MEN1 (0.41) | GAAMAPTSMN1; SMN2NPSR1TAAR1 | |
| SCHEMBL31181154 | 0.71 | MTNR1A (0.49) | GAAMAPTMTNR1AMTNR1BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |