SCHEMBL280388

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27981538	0.74	ALDH1A1 (0.64)	GRM6ALDH1A1MAPTSMN1; SMN2NPC1
	SCHEMBL28623302	0.71	ALDH1A1 (0.45)	ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
	SCHEMBL11156557	0.69	KDM4E (0.51)	ALDH1A1MAPTSMN1; SMN2ADORA3HPGD
	SCHEMBL279943	0.68	PTPN1 (0.53)	ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
	SCHEMBL15069718	0.67	KDR (0.47)	GRM6ALDH1A1MAPTSMN1; SMN2HPGD
	SCHEMBL28235717	0.66	ALDH1A1 (0.65)	GRM6ALDH1A1MAPTNPC1MEN1
	Benzophenone SCHEMBL260937	0.65	ALDH1A1 (0.82)	ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
	SCHEMBL9284389	0.64	MAPT (0.55)	ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
	SCHEMBL21369992	0.64	KDM4E (0.55)	GRM6ALDH1A1MAPTSMN1; SMN2NPC1
	SCHEMBL5682288	0.63	ATR (0.57)	ALDH1A1MAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.