SCHEMBL28038830

SCHEMBL28038830

Cc1cccc2cc3ccccc3c(Cl)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 11/20 0.52
ALDH1A1 P00352 7/20 0.52
HPGD P15428 4/20 0.52
HSD17B10 Q99714 4/20 0.52
CYP2A6 P11509 7/20 0.48
FYN P06241 2/20 0.46
ACHE P22303 2/20 0.46
AHR P35869 2/20 0.46
ERBB2 P04626 1/20 0.46
MAOA P21397 1/20 0.46
CES1 P23141 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 2/20 0.37
THRB P10828 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
GAA P10253 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28038829 0.85 CYP1A2 (0.40) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL10524314 0.80 CYP1A2 (0.55) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL7915000 0.77 ALDH1A1 (0.48) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL27615312 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL29839619 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL5747356 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL787069 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL30413091 0.76 CYP2A6 (0.56) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL632553 0.76 CYP2A6 (0.56) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
Methane SCHEMBL2329315 0.76 CYP1A2 (0.50) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981249-B Antimicrobe compound, their synthesis and its application 英国卫生部 2018-06-19 CN disclosed
CN-104981249-A Antimicrobial compounds, their synthesis and applications thereof SEC DEP FOR HEALTH 2015-10-14 CN disclosed