SCHEMBL5747356

SCHEMBL5747356

Cc1cccc2cc3ccccc3c(N)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 8/20 0.52
ALDH1A1 P00352 7/20 0.52
HPGD P15428 6/20 0.52
HSD17B10 Q99714 4/20 0.52
CYP2A6 P11509 4/20 0.48
ERBB2 P04626 1/20 0.46
FYN P06241 1/20 0.46
MAOA P21397 1/20 0.46
ACHE P22303 1/20 0.46
AHR P35869 1/20 0.46
KDM4E B2RXH2 4/20 0.45
LMNA P02545 3/20 0.45
POLB P06746 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PSMD14 O00487 1/20 0.45
MITF O75030 1/20 0.45
MAPT P10636 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
RAD52 P43351 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5746747 0.82 ALDH1A1 (0.56) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL11691006 0.80 ALDH1A1 (0.52) CYP1A2ALDH1A1HPGDHSD17B10ERBB2
SCHEMBL10524314 0.80 CYP1A2 (0.55) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL28038830 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL787069 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL27615312 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL29839619 0.77 CYP1A2 (0.52) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL5751362 0.77 CYP1A2 (0.42) CYP1A2ALDH1A1HPGDHSD17B10ERBB2
SCHEMBL5749966 0.77 EP300 (0.45) CYP1A2ALDH1A1HPGDHSD17B10ERBB2
SCHEMBL1264430 0.76 HTR2A (0.54) CYP1A2ALDH1A1HPGDHSD17B10CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105753631-B A kind of synthetic method of aromatic fluorine compound 沈阳化工研究院有限公司 2018-11-02 CN disclosed
EP-3214105-A1 PHOTOCURABLE COMPOSITION AND ANTHRACENE DERIVATIVE TO BE USED THEREIN National Institute of Advanced Industrial Science and Technology (JP) 2017-09-06 EP disclosed
CN-105753631-A Synthetic method of fluorine-containing aromatic compounds 沈阳化工研究院有限公司 2016-07-13 CN disclosed
CN-102161607-B Method for preparing fluorine-containing aromatic compound UNIV SOUTH CHINA AGRICULT 2014-07-30 CN disclosed
CN-102161607-A Method for preparing fluorine-containing aromatic compound UNIV SOUTH CHINA AGRICULT 2011-08-24 CN disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed