Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28039130

Cc1cccc2ccccc12.O=C(O)C(F)(F)F

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
CYP2A6 P11509 3/20 0.63
KDM4E B2RXH2 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP1A2 P05177 4/20 0.46
HPGD P15428 2/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
KCNJ11 Q14654 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
CDC25B P30305 1/20 0.41
PLK1 P53350 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL809258 0.86 CYP2A6 (0.77) ALDH1A1CYP2A6KDM4EHSD17B10CYP1A2
Trifluoroacetic Acid SCHEMBL28038831 0.84 ALDH1A1 (0.50) ALDH1A1CYP2A6KDM4EHSD17B10CYP1A2
Acetic Acid SCHEMBL31412758 0.84 ALDH1A1 (0.74) ALDH1A1CYP2A6KDM4EHSD17B10CYP1A2
Acetic Acid SCHEMBL1961579 0.84 ALDH1A1 (0.74) ALDH1A1CYP2A6KDM4EHSD17B10CYP1A2
Carbamic Acid SCHEMBL28454155 0.82 ALDH1A1 (0.71) ALDH1A1CYP2A6KDM4EHSD17B10CYP1A2
Acetic Acid SCHEMBL28004587 0.82 ALDH1A1 (0.71) ALDH1A1CYP2A6KDM4EHSD17B10CYP1A2
Acetone SCHEMBL27948247 0.82 CYP2A6 (0.77) ALDH1A1CYP2A6KDM4EHSD17B10CYP1A2
Phenanthrene SCHEMBL1839925 0.82 HSD17B10 (0.55) ALDH1A1CYP2A6KDM4EHSD17B10HPGD
Benzene SCHEMBL27993507 0.82 CYP2A6 (0.94) ALDH1A1CYP2A6HSD17B10CYP1A2HPGD
Trifluoroacetic Acid SCHEMBL1568331 0.81 PPARG (0.50) ALDH1A1KDM4EHSD17B10HPGDNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981249-B Antimicrobe compound, their synthesis and its application 英国卫生部 2018-06-19 CN disclosed
CN-104981249-A Antimicrobial compounds, their synthesis and applications thereof SEC DEP FOR HEALTH 2015-10-14 CN disclosed