Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28038831

Cc1cccc2cc3ccccc3cc12.O=C(O)C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
CYP1A2 P05177 4/20 0.50
HSD17B10 Q99714 3/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 3/20 0.45
GAA P10253 1/20 0.45
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CYP2A6 P11509 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GLA P06280 1/20 0.42
CYP2C19 P33261 1/20 0.42
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
PAX8 Q06710 1/20 0.38
PLA2G2D Q9UNK4 1/20 0.38
C1S P09871 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27930643 0.86 ALDH1A1 (0.56) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
Trifluoroacetic Acid SCHEMBL28039130 0.84 ALDH1A1 (0.63) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
Benzene SCHEMBL28779493 0.84 CYP1A2 (0.67) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
Anthracene SCHEMBL1558998 0.82 CES1 (0.50) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
SCHEMBL130783 0.82 CYP1A2 (0.69) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
Acrylic Acid SCHEMBL3862092 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
Methacrylic Acid SCHEMBL560416 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
Methacrylic Acid SCHEMBL6815378 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
SCHEMBL5400012 0.80 CYP1A2 (0.67) ALDH1A1CYP1A2HSD17B10HPGDKDM4E
SCHEMBL1309620 0.80 CYP1A2 (0.67) ALDH1A1CYP1A2HSD17B10HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981249-B Antimicrobe compound, their synthesis and its application 英国卫生部 2018-06-19 CN disclosed
CN-104981249-A Antimicrobial compounds, their synthesis and applications thereof SEC DEP FOR HEALTH 2015-10-14 CN disclosed