Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20087542 | 0.84 | NR4A1 (0.37) | ALDH1A1MAPTHPGDTDP1SETD7 | |
| SCHEMBL9626894 | 0.84 | TSHR (0.48) | KDM4ETSHRALDH1A1CA12CA1 | |
| SCHEMBL10609345 | 0.82 | TSHR (0.49) | TSHRALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL15764230 | 0.82 | KDM4E (0.40) | KDM4ETSHRALDH1A1CA12CA1 | |
| SCHEMBL20087543 | 0.81 | TDP1 (0.41) | TSHRALDH1A1MAPTTDP1ESR1 | |
| SCHEMBL6850637 | 0.78 | SETD7 (0.51) | KDM4ETSHRALDH1A1CA12CA1 | |
| SCHEMBL27913580 | 0.74 | ACHE (0.37) | ALDH1A1MAPTHPGDTDP1SMN1; SMN2 | |
| SCHEMBL28869014 | 0.73 | MAPT (0.39) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9655887 | 0.70 | ALDH1A1 (0.53) | KDM4ETSHRALDH1A1MAPTESR1 | |
| SCHEMBL28198484 | 0.70 | ALDH1A1 (0.41) | KDM4ETSHRALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010649-B | C-N axis chiral benzo [ C ] carbazole compound and synthesis method thereof | 商丘师范学院 | 2023-08-25 | — | — | CN | disclosed |
| CN-115010649-A | C-N axis chiral benzo [ C ] carbazole compound and synthesis method thereof | 商丘师范学院 | 2022-09-06 | — | — | CN | disclosed |
| CN-105152934-A | Method for catalytic asymmetric synthesis of axial chiral biaryl diphenol | UNIV SOUTH SCIENCE & TECHNOLOGY CHINA | 2015-12-16 | — | — | CN | disclosed |