Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MMP12 | P39900 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844243 | 0.79 | TDP1 (0.54) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL7765576 | 0.72 | MAPT (0.56) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL20087542 | 0.72 | NR4A1 (0.37) | MAPTKMT2AALDH1A1MEN1MAOA | |
| SCHEMBL7760184 | 0.71 | ALDH1A1 (0.56) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL6702870 | 0.71 | MMP1 (0.54) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL30429390 | 0.71 | ALDH1A1 (0.56) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL6176778 | 0.70 | ALDH1A1 (0.55) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL20087543 | 0.70 | TDP1 (0.41) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL31554190 | 0.70 | MAPT (0.57) | MMP1MMP2MMP9MMP12MAPT | |
| SCHEMBL10800307 | 0.70 | ALDH1A1 (0.56) | MMP1MMP2MMP9MMP12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105152934-A | Method for catalytic asymmetric synthesis of axial chiral biaryl diphenol | UNIV SOUTH SCIENCE & TECHNOLOGY CHINA | 2015-12-16 | — | — | CN | disclosed |