Acrylamide

Acrylamide

SCHEMBL28039196

C=CC(N)=O.CNC(N)=O

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.65
ALDH1A1 P00352 4/20 0.65
FGFR4 P22455 1/20 0.65
LMNA P02545 4/20 0.35
NFKB1 P19838 2/20 0.35
BLM P54132 2/20 0.35
PMP22 Q01453 2/20 0.35
CYP1A2 P05177 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
THPO P40225 1/20 0.35
CA2 P00918 1/20 0.35
CYP3A4 P08684 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35
CRBN Q96SW2 1/20 0.35
TDP1 Q9NUW8 2/20 0.32
MAPK1 P28482 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL659888 0.88
Acrylamide SCHEMBL27788827 0.86 ALDH1A1 (0.61) TSHRALDH1A1FGFR4LMNABLM
Acrylamide SCHEMBL5694435 0.85 TSHR (0.69) TSHRALDH1A1FGFR4LMNANFKB1
Acrylamide SCHEMBL20561989 0.85 TSHR (0.69) TSHRALDH1A1FGFR4LMNANFKB1
Acrylamide SCHEMBL5694442 0.85
Acrylamide SCHEMBL1094216 0.83 TSHR (0.58) TSHRALDH1A1FGFR4LMNATDP1
SCHEMBL28368514 0.83 TSHR (0.43) TSHRALDH1A1FGFR4LMNANFKB1
Acrylamide SCHEMBL20515124 0.82 ALDH1A1 (0.65) TSHRALDH1A1FGFR4LMNABLM
Formaldehyde SCHEMBL27955693 0.81
Acrylamide SCHEMBL943492 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105164169-A Preparation of high molecular weight, functionalized poly(meth) acrylamide polymers by transamidation DOW GLOBAL TECHNOLOGIES INC 2015-12-16 CN claimed
CN-105164169-A Preparation of high molecular weight, functionalized poly(meth) acrylamide polymers by transamidation DOW GLOBAL TECHNOLOGIES INC 2015-12-16 CN disclosed