Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202111 | 0.82 | HPGD (0.49) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL7002987 | 0.82 | HPGD (0.49) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL7005690 | 0.82 | HPGD (0.49) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL12486284 | 0.82 | HSD17B10 (0.48) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL3434909 | 0.82 | HSD17B10 (0.48) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL1427524 | 0.82 | HSD17B10 (0.48) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL14664469 | 0.81 | HSD17B10 (0.47) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL12741121 | 0.81 | HSD17B10 (0.47) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL4474810 | 0.81 | HSD17B10 (0.47) | HSD17B10HPGDEPHX1ALDH1A1PREP | |
| SCHEMBL3799824 | 0.81 | HSD17B10 (0.47) | HSD17B10HPGDEPHX1ALDH1A1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955833-A | C17-alkanediyl and alkenediyl derivatives of oleanolic acid and methods of use thereof | REATA PHARMACEUTICALS INC | 2015-09-30 | — | — | CN | disclosed |