Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ASGR1 | P07306 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.30 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.30 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889397 | 1.00 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1PKMMAPK1KMT2A | |
| SCHEMBL7567193 | 1.00 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1PKMMAPK1KMT2A | |
| SCHEMBL1743867 | 0.89 | — | — | |
| SCHEMBL7136442 | 0.89 | ASGR1 (0.33) | ALDH1A1L3MBTL1ASGR1 | |
| SCHEMBL5179161 | 0.89 | ASGR1 (0.33) | ALDH1A1L3MBTL1ASGR1 | |
| SCHEMBL2803932 | 0.89 | — | — | |
| SCHEMBL8581103 | 0.89 | ASGR1 (0.33) | ALDH1A1L3MBTL1ASGR1 | |
| SCHEMBL12560770 | 0.88 | MAPK1 (0.40) | ALDH1A1L3MBTL1PKMMAPK1KMT2A | |
| SCHEMBL9786210 | 0.85 | ALDH1A1 (0.32) | ALDH1A1CA1CA2 | |
| SCHEMBL9786206 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6168934-B1 | EFFICIENT GLYCOSYLATION BY MIXING ACCEPTOR SACCHARIDE, DONOR MONOSACCHARIDE, ACTIVATING NUCLEOTIDE, ACTIVATED DONOR MONOSACCHARIDE REGENERATING SYSTEM, PYROPHOSPHATE SCAVENGER, AND GLYCOSYLTRANSFERASE IN AN AQUEOUS MEDIUM | THE SCRIPPS RESEARCH INSTITUTE | 2001-01-02 | — | — | US | disclosed |
| EP-0576592-B1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | SCRIPPS RESEARCH INST (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5759823-A | MIXING IN AQUEOUS MEDIUM ACTIVATED DONOR MONOSACCHARIDE WITH ACCEPTOR SACCHARIDE IN PRESENCE OF GLYCOSYLTRANSFERASE, MAINTAINING TO GLYCOSYLATE ACCEPTOR SACCHARIDE | SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0570682-B1 | Synthetic lipid A glycoconjugate antigens for use in vaccines | AMERICAN CYANAMID CO (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5593887-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-01-14 | — | — | US | disclosed |
| US-5461143-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0576592-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0570682-A1 | Synthetic lipid A glycoconjugate antigens for use in vaccines | AMERICAN CYANAMID COMPANY (US) | 1993-11-24 | — | — | EP | disclosed |
| WO-1992016640-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-10-01 | — | — | WO | disclosed |