Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL2352840 | 0.84 | TSHR (0.42) | TSHRALDH1A1KDM4EHSD17B10MGAM | |
| SCHEMBL31644470 | 0.80 | PAOX (0.56) | TSHRALDH1A1PAOXLMNA | |
| 1,4-Butanediol SCHEMBL28968699 | 0.79 | CYP4A11 (0.42) | TSHRALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL9683861 | 0.79 | TSHR (0.38) | TSHRALDH1A1KDM4EHSD17B10MGAM | |
| Ethylene Glycol SCHEMBL9682292 | 0.79 | TSHR (0.38) | TSHRALDH1A1KDM4EHSD17B10MGAM | |
| Alcohol SCHEMBL11246505 | 0.78 | — | — | |
| Hydrazine SCHEMBL29112721 | 0.77 | — | — | |
| Monoethanolamine SCHEMBL9293909 | 0.77 | — | — | |
| SCHEMBL4971363 | 0.77 | — | — | |
| SCHEMBL4748477 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1KDM4EHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-204865499-U | Methyl nitrite's waste gas treatment system | ENGINEERING DESIGN RES INST CO LTD OF EAST CHINA UNIVERSITY | 2015-12-16 | — | — | CN | disclosed |