Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663537 | 0.80 | GABRA1 (0.32) | ATMALDH1A1 | |
| SCHEMBL13718969 | 0.77 | CYP2A6 (0.36) | TDP1L3MBTL1MAPTLMNAGAA | |
| SCHEMBL266575 | 0.74 | TDP1 (0.69) | TDP1L3MBTL1SIRT5ATMKMT2A | |
| SCHEMBL30716622 | 0.74 | TDP1 (0.69) | TDP1L3MBTL1SIRT5ATMKMT2A | |
| SCHEMBL18791620 | 0.73 | CYP1A2 (0.50) | TDP1L3MBTL1MAPTLMNAPOLB | |
| SCHEMBL4319548 | 0.73 | KDM4E (0.42) | L3MBTL1MAPTLMNAPOLBGAA | |
| SCHEMBL297548 | 0.72 | TDP1 (0.61) | TDP1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3477677 | 0.72 | L3MBTL1 (0.33) | L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8382670 | 0.72 | IDO1 (0.35) | — | |
| SCHEMBL7746016 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955332-B | The method of preventing and treating arthropod insect | 住友化学株式会社 | 2017-03-29 | — | — | CN | disclosed |
| CN-104955332-A | Method for controlling arthropod pest | SUMITOMO CHEMICAL CO | 2015-09-30 | — | — | CN | disclosed |