Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920402 | 0.83 | MAPK1 (0.47) | MAOADYRK1AMAPK1GPR132F9 | |
| SCHEMBL7245835 | 0.82 | NOS3 (0.46) | MAOAMAPK1BRD4CREBBPIKBKB | |
| SCHEMBL539028 | 0.82 | MAOB (0.53) | MAOAMAPK1LMNA | |
| SCHEMBL864294 | 0.79 | MAPK1 (0.52) | MAOAMAPK1GPR132HTR1ADRD2 | |
| SCHEMBL28011530 | 0.78 | MAPK1 (0.64) | MAPK1GPR132LMNAF9F10 | |
| SCHEMBL13452125 | 0.78 | MAPK1 (0.57) | MAOADYRK1AMAPK1GPR132HTR1A | |
| SCHEMBL28048524 | 0.76 | MAPK1 (0.64) | MAOADYRK1AMAPK1GPR132F9 | |
| SCHEMBL8124450 | 0.76 | LMNA (0.61) | LMNAGRM5 | |
| SCHEMBL171895 | 0.75 | MAPK1 (0.56) | MAOADYRK1AMAPK1GPR132GRM5 | |
| SCHEMBL791886 | 0.75 | MAOB (0.66) | MAPK1GPR132LMNAHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459388-B | Novel furanone derivative | CARNA BIOSCIENCES, INC. (JP) | 2015-11-25 | — | — | CN | disclosed |