Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 2/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039663 | 0.87 | IDO1 (0.37) | IDO1MMP2MMP3HTTALDH1A1 | |
| SCHEMBL28141976 | 0.78 | SCN4A (0.52) | SCN4A | |
| Hydrochloric Acid SCHEMBL7649730 | 0.78 | LOXL2 (0.42) | ALDH1A1LOXL2SCN4ACA1CA2 | |
| SCHEMBL28039667 | 0.74 | ALDH1A1 (0.44) | IDO1ALDH1A1KDM4EMAPTLOXL2 | |
| SCHEMBL14448531 | 0.72 | LOXL2 (0.43) | IDO1MMP3ALDH1A1KDM4EGAA | |
| SCHEMBL5900978 | 0.72 | LOXL2 (0.43) | IDO1MMP3ALDH1A1KDM4EGAA | |
| SCHEMBL8514968 | 0.72 | LOXL2 (0.43) | IDO1MMP3ALDH1A1KDM4EGAA | |
| SCHEMBL8986283 | 0.71 | IDO1 (0.47) | IDO1MMP3HTTGAAL3MBTL1 | |
| SCHEMBL1310869 | 0.70 | KDM4E (0.55) | MMP2HTTKDM4EGAAMAPT | |
| SCHEMBL13991118 | 0.70 | KDM4E (0.55) | MMP2HTTKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106892942-B | A kind of preparation method of beta-amido ethylphosphonic acid derivative | 苏州大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-105017312-A | Preparation method of beta-aminoethyl phosphono derivative | UNIV SOOCHOW | 2015-11-04 | — | — | CN | disclosed |