Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20172587 | 0.91 | SMN1; SMN2 (0.52) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL13385087 | 0.82 | PDE4B (0.48) | SMN1; SMN2ALDH1A1MAPTALOX5APFEN1 | |
| SCHEMBL5463881 | 0.81 | SMN1; SMN2 (0.66) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL17194893 | 0.81 | L3MBTL1 (0.51) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL29496937 | 0.81 | SMN1; SMN2 (0.66) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL28128888 | 0.80 | SMN1; SMN2 (0.47) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL27295955 | 0.80 | SMN1; SMN2 (0.47) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL29693912 | 0.78 | NPC1 (0.46) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL27992763 | 0.78 | KDM4E (0.52) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL3364759 | 0.78 | KDM4E (0.56) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961728-A | Preparation method and application of pyridinyl methoxybiphenyl structure-containing pyrazole oxime ester compound | UNIV NANTONG | 2015-10-07 | — | — | CN | disclosed |
| CN-104961728-A | Preparation method and application of pyridinyl methoxybiphenyl structure-containing pyrazole oxime ester compound | UNIV NANTONG | 2015-10-07 | — | — | CN | disclosed |