Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039706 | 0.91 | NPC1 (0.47) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL5463881 | 0.89 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL17194893 | 0.89 | L3MBTL1 (0.51) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL29496937 | 0.89 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL27295955 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL28128888 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL20150104 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL18415019 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL30360634 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL8498483 | 0.84 | ERN1 (0.49) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396801-B1 | OLED DEVICE WITH FLUORANTHENE-MACROCYCLIC MATERIALS | GLOBAL OLED TECHNOLOGY LLC (US) | 2018-05-23 | — | — | EP | disclosed |