Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061340 | 0.72 | GPR35 (0.53) | GPR35HCAR2PKMNPSR1TSHR | |
| SCHEMBL17353542 | 0.71 | GPR35 (0.56) | GPR35RARB | |
| SCHEMBL4753776 | 0.70 | GPR35 (0.68) | GPR35PKMNPSR1RXFP1TSHR | |
| SCHEMBL2727696 | 0.70 | GPR35 (0.66) | GPR35PKMNPSR1RXFP1TSHR | |
| SCHEMBL6065355 | 0.69 | GPR35 (0.43) | GPR35RARB | |
| SCHEMBL2225099 | 0.69 | CYP3A4 (0.44) | GPR35PKMNPSR1RXFP1PTPN1 | |
| SCHEMBL25195925 | 0.67 | GPR35 (0.53) | GPR35PKMNPSR1RXFP1TSHR | |
| SCHEMBL406992 | 0.67 | GPR35 (0.70) | GPR35PKMNPSR1RXFP1 | |
| SCHEMBL1030733 | 0.66 | GPR35 (0.64) | GPR35HCAR2RARB | |
| SCHEMBL27512413 | 0.66 | PKM (0.58) | GPR35HCAR2PKMNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073761-A | Substituted silaxanthenium red to near-infrared fluorochromes for in vitro and in vivo imaging and detection | VISEN MEDICAL INC | 2015-11-18 | — | — | CN | disclosed |