Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823525 | 0.88 | CYP2C19 (0.45) | POLBCYP2C19HPGDRIPK1LMNA | |
| SCHEMBL27569205 | 0.81 | POLB (0.46) | KMT2AMAPTPOLBCYP2C19NPC1 | |
| SCHEMBL28013833 | 0.80 | POLB (0.51) | POLBCYP2C19NPC1CTSCHPGD | |
| SCHEMBL28013248 | 0.79 | HTT (0.44) | KMT2AMAPTPOLBCYP2C19NPC1 | |
| SCHEMBL17009210 | 0.79 | POLB (0.50) | KMT2APOLBCYP2C19NPC1MEN1 | |
| SCHEMBL2845811 | 0.77 | MAPT (0.55) | KMT2AMAPTCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL6533651 | 0.76 | BLM (0.50) | KMT2AMAPTPOLBCYP2C19MEN1 | |
| SCHEMBL17439463 | 0.75 | KMT2A (0.43) | KMT2AMAPTNPC1MEN1RAB9A | |
| SCHEMBL28013253 | 0.75 | RIPK1 (0.49) | KMT2AMAPTPOLBCYP2C19NPC1 | |
| SCHEMBL4485884 | 0.74 | RIPK1 (0.50) | POLBCYP2C19HPGDRIPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175392-A | Carboxylic acid compounds containing thiophene structures and amide compounds containing thiophene structures and preparation method for carboxylic acid compounds and amide compounds | UNIV HUNAN | 2015-12-23 | — | — | CN | disclosed |