SCHEMBL17439463

SCHEMBL17439463

CC(Cc1nccs1)(C(N)=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.42
SLC6A3 Q01959 1/20 0.39
NR3C2 P08235 1/20 0.38
NR3C1 P04150 1/20 0.38
CTSA P10619 1/20 0.37
RBBP9 O75884 1/20 0.36
ACKR3 P25106 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ADORA2A P29274 1/20 0.35
SLC22A2 O15244 1/20 0.35
SLC22A1 O15245 1/20 0.35
PGR P06401 1/20 0.35
THRB P10828 1/20 0.35
ADRB3 P13945 1/20 0.35
OPRK1 P41145 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470115 0.79 FDPS (0.41) KMT2AMEN1SLC6A3ADORA2ACYP3A4
SCHEMBL29020384 0.78 SLC6A3 (0.41) KMT2AMEN1SLC6A3NPC1RAB9A
SCHEMBL10411485 0.76 MEN1 (0.43) KMT2AMEN1SLC6A3NR3C1CTSA
SCHEMBL28040029 0.75 KMT2A (0.46) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL17439466 0.75 SMN1; SMN2 (0.41) KMT2AMEN1NR3C1KDM4ETSHR
SCHEMBL2845811 0.74 MAPT (0.55) KMT2AMAPTCYP3A4
SCHEMBL1458946 0.72 KMT2A (0.46) KMT2AMEN1MAPTNR3C1CTSA
SCHEMBL2202821 0.71 MAPT (0.43) KMT2AMAPTNR3C2RAB9ACYP3A4
SCHEMBL2030597 0.70 MAPT (0.59) KMT2AMAPTKDM4EKCNH2CYP3A4
SCHEMBL1024478 0.70 MAPT (0.59) KMT2AMAPTNR3C2KDM4EKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160015614-A1 COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND UV-FILTER SUBSTANCES BEIERSDORF AG (DE) 2016-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160015614-A1 COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND UV-FILTER SUBSTANCES TYR, NACA, AADAC KMT2A 1265/4885MEN1 3268/4885MAPT 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.