Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040572 | 0.92 | CALM1 (0.55) | CALM1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11684891 | 0.82 | CALM1 (0.54) | CALM1ATMKDM4EPOLB | |
| SCHEMBL28040573 | 0.82 | TUBB4A (0.50) | CALM1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29689431 | 0.81 | TUBB4A (0.74) | CALM1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2759507 | 0.81 | ATM (0.63) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL20696534 | 0.81 | TUBB4A (0.74) | CALM1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20970875 | 0.81 | HTR2A (0.73) | CYP19A1ATMKDM4E | |
| SCHEMBL27584364 | 0.81 | ATM (0.54) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL12338366 | 0.81 | HTR2A (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13991781 | 0.80 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | claimed |
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |