Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477104 | 0.92 | SLC6A4 (0.59) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL248440 | 0.92 | SLC6A4 (0.59) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL8747043 | 0.85 | MTNR1A (0.50) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL3968194 | 0.83 | SLC6A4 (0.56) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL497994 | 0.83 | SLC6A4 (0.56) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL24034816 | 0.82 | SLC6A4 (0.51) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL28701417 | 0.82 | SLC6A4 (0.51) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL7650624 | 0.82 | SLC6A4 (0.55) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL28695042 | 0.82 | SLC6A4 (0.51) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL168782 | 0.82 | SLC6A4 (0.54) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175414-A | Imidazole [4,5-b] pyridine mercaptoacetamide derivative as well as preparation method and application thereof | UNIV SHANDONG | 2015-12-23 | — | — | CN | claimed |
| CN-105175414-A | Imidazole [4,5-b] pyridine mercaptoacetamide derivative as well as preparation method and application thereof | UNIV SHANDONG | 2015-12-23 | — | — | CN | disclosed |