Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefaclor Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.98 |
| ▸ | MEN1 | O00255 | 5/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.98 |
| ▸ | HPGD | P15428 | 3/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.98 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.98 |
| ▸ | LMNA | P02545 | 2/20 | 0.98 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.98 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.98 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.98 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefaclor Anhydrous SCHEMBL2884379 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL956758 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL2370228 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL27866433 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL9753635 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL23611123 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL33539 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL1006419 | 0.99 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL8478823 | 0.99 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL16072812 | 0.99 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085549-B | The pharmaceutical composition and its preparation of a kind of Cefaclor compound, the compound and bromhexine hydrochloride | 山东罗欣药业集团股份有限公司 | 2017-08-15 | — | — | CN | claimed |
| CN-105085549-A | Cefaclor compound, medicine composition of cefaclor compound and bromhexine hydrochloride, and preparation of cefaclor compound | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-25 | — | — | CN | claimed |
| CN-105085549-B | The pharmaceutical composition and its preparation of a kind of Cefaclor compound, the compound and bromhexine hydrochloride | 山东罗欣药业集团股份有限公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-105085549-B | The pharmaceutical composition and its preparation of a kind of Cefaclor compound, the compound and bromhexine hydrochloride | 山东罗欣药业集团股份有限公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-105085549-A | Cefaclor compound, medicine composition of cefaclor compound and bromhexine hydrochloride, and preparation of cefaclor compound | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-25 | — | — | CN | disclosed |
| CN-105085549-A | Cefaclor compound, medicine composition of cefaclor compound and bromhexine hydrochloride, and preparation of cefaclor compound | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-25 | — | — | CN | disclosed |