Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefaclor Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.98 |
| ▸ | MEN1 | O00255 | 5/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.98 |
| ▸ | HPGD | P15428 | 3/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.98 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.98 |
| ▸ | LMNA | P02545 | 2/20 | 0.98 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.98 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.98 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.98 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefaclor Anhydrous SCHEMBL2884379 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL28040138 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL2370228 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL27866433 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL9753635 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL23611123 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL33539 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL1006419 | 0.99 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL8478823 | 0.99 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT | |
| Cefaclor Anhydrous SCHEMBL16072812 | 0.99 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4ECYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113817440-B | Compound hydrate accelerant, application and gas storage and transportation method | 中国石油化工股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-113817440-A | Compound hydrate accelerant, application and gas storage and transportation method | 中国石油化工股份有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-111678997-A | Method for detecting residual medicine of anti-tumor medicine packaging container and application thereof | 四川省人民医院 | 2020-09-18 | — | — | CN | claimed |
| CN-111665074-A | Method for detecting drug leakage of intelligent dispensing system of robot | 四川省人民医院 | 2020-09-15 | — | — | CN | claimed |
| CN-109694381-A | A kind of cefaclor hydrate and preparation method thereof | 天津大学 | 2019-04-30 | — | — | CN | claimed |
| EP-3452018-A2 | EFFERVESCENT FORMULATIONS COMPRISING CEFACLOR AND CLAVULANIC ACID AS ACTIVE AGENTS | Bilgic, Mahmut (TR) | 2019-03-13 | — | — | EP | claimed |
| EP-2528589-A2 | STABLE EFERVESCENT FORMULATIONS COMPRISING CEFACLOR | Bilgic, Mahmut (TR) | 2012-12-05 | — | — | EP | claimed |
| CN-101805357-B | Cefaclor compound and novel preparation method thereof | LINGGANG TAO | 2012-01-11 | — | — | CN | claimed |
| WO-2011093832-A2 | STABLE EFERVESCENT FORMULATIONS COMPRISING CEFACLOR | BILGIC MAHMUT (TR) | 2011-08-04 | — | — | WO | claimed |
| WO-2011093826-A2 | EFFERVESCENT FORMULATIONS COMPRISING CEFACLOR AND CLAVULANIC ACID AS ACTIVE AGENTS | BILGIC MAHMUT (TR) | 2011-08-04 | — | — | WO | claimed |
| CN-1982315-A | Synthesis of cefaclor | CHEN SHUMING (CN) | 2007-06-20 | — | — | CN | claimed |
| CN-1830982-A | Method for recovering cefaclor | ZHONGLIAN CHEMICAL PHARMACEUTI (CN) | 2006-09-13 | — | — | CN | claimed |
| EP-1180022-A4 | PROCESS FOR PREPARING PHARMACEUTICAL BULK MATERIAL HAVING UNIFORM DISSOLUTION | LILLY CO ELI (US) | 2004-01-07 | — | — | EP | claimed |
| US-6596307-B1 | Crystalline cefaclor with reduced water content | ELI LILLY AND COMPANY | 2003-07-22 | — | — | US | claimed |
| EP-1180022-A1 | PROCESS FOR PREPARING PHARMACEUTICAL BULK MATERIAL HAVING UNIFORM DISSOLUTION | ELI LILLY AND COMPANY (US) | 2002-02-20 | — | — | EP | claimed |
| WO-2000069417-A1 | PROCESS FOR PREPARING PHARMACEUTICAL BULK MATERIAL HAVING UNIFORM DISSOLUTION | ELI LILLY AND COMPANY (US) | 2000-11-23 | — | — | WO | claimed |
| EP-0547646-B1 | Crystalline form of a cephalosporin antibiotic | OPOS BIOCHIMICA SRL (IT) | 1998-06-03 | — | — | EP | claimed |
| US-5693790-A | FORMED BY TREATING CEFACLOR WITH MINERAL OR ORGANIC ACID IN MIXTURE OF WATER AND ALCOHOL | BIOCHIMICA OPOS SPA (IT) | 1997-12-02 | — | — | US | claimed |
| US-5589593-A | CRYSTALLIZATION OF CEFACLOR AND FORMATION OF THE HYDRATE, STABILITY | BIOCHIMICA OPOS SPA (IT) | 1996-12-31 | — | — | US | claimed |
| EP-0547646-A2 | Crystalline form of a cephalosporin antibiotic | BIOCHIMICA OPOS SPA (IT) | 1993-06-23 | — | — | EP | claimed |