Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525854 | 0.88 | LMNA (0.56) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL6582665 | 0.87 | LMNA (0.52) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL7449135 | 0.83 | POLB (0.63) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL11974037 | 0.83 | POLB (0.58) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL30802296 | 0.82 | SMN1; SMN2 (0.51) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL15048844 | 0.82 | LMNA (0.51) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL7339506 | 0.82 | LMNA (0.61) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL184778 | 0.82 | LMNA (0.61) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL19279385 | 0.82 | LMNA (0.50) | THRBATML3MBTL1LMNAPOLB | |
| SCHEMBL30297461 | 0.82 | LMNA (0.50) | THRBATML3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085515-A | Hydrazide compound as blood coagulation factor Xa inhibitor | NANJING MINGDE NEW DRUG RES AND DEV CO LTD | 2015-11-25 | — | — | CN | disclosed |