Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040139 | 0.87 | THRB (0.63) | LMNAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL3174479 | 0.86 | L3MBTL1 (0.67) | LMNAPOLBL3MBTL1THRBATM | |
| SCHEMBL21757648 | 0.85 | SMN1; SMN2 (0.48) | LMNAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL525854 | 0.84 | LMNA (0.56) | LMNAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL14368354 | 0.81 | L3MBTL1 (0.60) | LMNAPOLBL3MBTL1THRBATM | |
| SCHEMBL5500990 | 0.81 | LMNA (0.56) | LMNAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL31540784 | 0.81 | LMNA (0.50) | LMNAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL7449135 | 0.80 | POLB (0.63) | LMNAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL30802296 | 0.79 | SMN1; SMN2 (0.51) | LMNAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL15048844 | 0.79 | LMNA (0.51) | LMNAPOLBSMN1; SMN2L3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091856-A2 | BETA-LACTAMASE INHIBITORS | MERCK & CO., INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| EP-1455788-A1 | 1-GLYCINYL-4-AMINOMETHYL-PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003049737-A1 | CHEMICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |