Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040533 | 0.87 | KMT2A (0.47) | SLC40A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL28040537 | 0.77 | PPARA (0.38) | KMT2ASMN1; SMN2KDM4ERAB9AALDH1A1 | |
| SCHEMBL28040727 | 0.76 | SMN1; SMN2 (0.36) | KMT2AMAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL28818995 | 0.76 | KDR (0.44) | SLC40A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL28475373 | 0.72 | KMT2A (0.53) | SLC40A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8102961 | 0.69 | TDP1 (0.66) | SLC40A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL28013840 | 0.68 | POLB (0.47) | SLC40A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL28040062 | 0.68 | LMNA (0.33) | KMT2ASMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL28160493 | 0.68 | POLB (0.46) | SLC40A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL1859001 | 0.66 | SLC40A1 (0.70) | SLC40A1KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175392-A | Carboxylic acid compounds containing thiophene structures and amide compounds containing thiophene structures and preparation method for carboxylic acid compounds and amide compounds | UNIV HUNAN | 2015-12-23 | — | — | CN | disclosed |