Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376113 | 0.87 | METAP1 (0.57) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL28126153 | 0.87 | METAP1 (0.57) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL577480 | 0.87 | PGR (0.49) | TDP2PGRCYP17A1SRD5A1CA1 | |
| SCHEMBL40823 | 0.87 | METAP1 (0.57) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| Ammonia Solution, Strong SCHEMBL28144371 | 0.84 | METAP1 (0.55) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL27619851 | 0.84 | METAP1 (0.55) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL4826135 | 0.82 | METAP1 (0.53) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL29569917 | 0.80 | METAP1 (0.52) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL9811056 | 0.80 | PGR (0.49) | TDP2PGRCYP17A1SRD5A2CA1 | |
| SCHEMBL3129344 | 0.80 | METAP1 (0.52) | METAP1TDP2PGRSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037167-B | A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application | 华南理工大学 | 2017-03-01 | — | — | CN | claimed |
| CN-105037167-A | Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof | UNIV SOUTH CHINA TECH | 2015-11-11 | — | — | CN | claimed |
| CN-105037167-B | A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application | 华南理工大学 | 2017-03-01 | — | — | CN | disclosed |
| CN-105037167-A | Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof | UNIV SOUTH CHINA TECH | 2015-11-11 | — | — | CN | disclosed |