Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314796 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2PTGER1PLA2G4AKDM4CALDH1A1 | |
| SCHEMBL22660142 | 0.78 | CYP1A2 (0.45) | ALDH1A1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL26057095 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2PTGER1PLA2G4AKDM4CALDH1A1 | |
| SCHEMBL2978805 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL31373302 | 0.76 | KDM4C (0.58) | SMN1; SMN2PTGER1PLA2G4AKDM4CALDH1A1 | |
| SCHEMBL31373301 | 0.76 | KDM4C (0.58) | SMN1; SMN2PTGER1PLA2G4AKDM4CALDH1A1 | |
| SCHEMBL29625285 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2PTGER1PLA2G4AKDM4CALDH1A1 | |
| SCHEMBL932824 | 0.76 | ALDH1A1 (0.55) | SMN1; SMN2PLA2G4AKDM4CALDH1A1KMT2A | |
| SCHEMBL6275635 | 0.75 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL15202347 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2PTGER1PLA2G4AKDM4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008331-B | Act on multiple prostaglandin receptors, produce the compound of general anti-inflammatory response | 阿勒根公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-103038219-B | Act on Prostaglandins receptor thus obtain the compound of general anti-inflammatory response | 阿勒根公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105008331-A | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN INC | 2015-10-28 | — | — | CN | disclosed |