Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26057095 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL31373301 | 0.80 | KDM4C (0.58) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL932824 | 0.80 | ALDH1A1 (0.55) | SMN1; SMN2KDM4CPLA2G4AALDH1A1KMT2A | |
| SCHEMBL31373302 | 0.80 | KDM4C (0.58) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL29625285 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL28040263 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL15202347 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL167425 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL1431755 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 | |
| SCHEMBL6877868 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2PTGER1KDM4CPLA2G4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090522-A1 | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives | VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090522-A1 | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives | ITPA, IDO1, IDO2 | SMN1; SMN2 4726/4885PTGER1 2184/4885KDM4C 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.