Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576651 | 0.80 | HDAC6 (0.34) | HDAC1HDAC2HDAC6 | |
| SCHEMBL138266 | 0.77 | GAA (0.39) | GAAEPHX1HPGDBTKHSD11B1 | |
| SCHEMBL4552317 | 0.75 | HSD11B1 (0.44) | GAAEPHX1HPGDBTKHSD11B1 | |
| SCHEMBL1722706 | 0.75 | GAA (0.38) | GAAEPHX1HPGDBTKHSD11B1 | |
| SCHEMBL24292459 | 0.74 | BTK (0.38) | GAAEPHX1HPGDBTKHSD11B1 | |
| SCHEMBL871258 | 0.74 | GAA (0.37) | GAAEPHX1HPGDBTKHSD11B1 | |
| SCHEMBL27879410 | 0.73 | CA14 (0.37) | HSD11B1HDAC1HDAC2HDAC6 | |
| SCHEMBL27500836 | 0.73 | MEN1 (0.42) | GAAEPHX1HPGDBTKALDH1A1 | |
| SCHEMBL18586243 | 0.73 | GAA (0.35) | GAAEPHX1HPGDBTKHSD11B1 | |
| SCHEMBL13943891 | 0.73 | HSD11B1 (0.45) | GAAEPHX1HPGDBTKHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101443350-B | Macrocyclic compounds as antiviral agents | MSD ITALIA S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |