SCHEMBL138266

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24292459	0.98	BTK (0.38)	GAATSHREPHX1HSD11B1HPGD
	SCHEMBL24292449	0.91	HSD11B1 (0.37)	GAATSHREPHX1HSD11B1HPGD
	SCHEMBL27630283	0.90	SLC6A4 (0.39)	GAATSHREPHX1HSD11B1TRPM8
	SCHEMBL27740053	0.88	SLC6A4 (0.38)	GAATSHREPHX1BTKTRPM8
	SCHEMBL25104905	0.86	SLC6A4 (0.47)	—
	SCHEMBL13144562	0.85	SLC6A4 (0.38)	BTK
	SCHEMBL24292463	0.85	CHRM2 (0.37)	GAATSHREPHX1HSD11B1BTK
	SCHEMBL25031797	0.84	BTK (0.38)	GAATSHREPHX1HPGDBTK
	SCHEMBL879530	0.83	TSHR (0.36)	GAATSHREPHX1HSD11B1PHGDH
	SCHEMBL4552317	0.82	HSD11B1 (0.44)	GAATSHREPHX1HSD11B1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 923 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.