SCHEMBL28040285

SCHEMBL28040285

Cc1cccc(O[SiH](C)C)c1N=C(c1ccccc1)c1cnccn1.[H+]

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 4/20 0.41
TBXAS1 P24557 4/20 0.41
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 2/20 0.34
NOTUM Q6P988 1/20 0.34
TSHR P16473 1/20 0.34
KMT2A Q03164 2/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499260 0.99 TBXA2R (0.42) TBXA2RTBXAS1MAPTSMN1; SMN2ALDH1A1
SCHEMBL17499811 0.87 AGTR1 (0.45) MAPTKDM4EL3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL16097382 0.86 TBXA2R (0.44) TBXA2RTBXAS1MAPTKDM4EL3MBTL1
SCHEMBL28858395 0.85 KMT2A (0.37) MAPTKDM4EL3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL16096455 0.84 TBXA2R (0.42) TBXA2RTBXAS1MAPTSMN1; SMN2ALDH1A1
SCHEMBL17499417 0.84 KMT2A (0.38) MAPTKDM4EL3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL17499802 0.82 TBXA2R (0.36) TBXA2RMAPTKDM4ESMN1; SMN2ALDH1A1
SCHEMBL17499174 0.82 TBXA2R (0.45) TBXA2RTBXAS1MAPTKDM4ESMN1; SMN2
SCHEMBL28040301 0.82 TBXA2R (0.41) TBXA2RTBXAS1MAPTSMN1; SMN2ALDH1A1
SCHEMBL17499206 0.81 TBXA2R (0.42) TBXA2RTBXAS1MAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209268-B Heterocyclic imine functionalized polymers 株式会社普利司通 2018-05-04 CN disclosed
CN-105209268-A Heterocyclic imine functionalized polymers BRIDGESTONE CORP 2015-12-30 CN disclosed