Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | MITF | O75030 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499811 | 0.88 | AGTR1 (0.45) | AGTR1LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16104921 | 0.86 | HTT (0.40) | TBXA2RAGTR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16095840 | 0.84 | TBXA2R (0.36) | TBXA2RAGTR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL17499260 | 0.83 | TBXA2R (0.42) | TBXA2RSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL28040285 | 0.82 | TBXA2R (0.41) | TBXA2RSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL17499655 | 0.82 | PLAU (0.33) | MAPTKDM4EPLAU | |
| SCHEMBL17499671 | 0.82 | TBXA2R (0.39) | TBXA2RAGTR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16101685 | 0.80 | — | — | |
| SCHEMBL16096560 | 0.80 | ESR2 (0.40) | TBXA2RLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16098687 | 0.78 | ALDH1A1 (0.42) | LMNAHTTSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |