Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563510 | 0.89 | APP (0.55) | APPKDM4EALDH1A1LMNAL3MBTL1 | |
| Bromide SCHEMBL28159616 | 0.87 | APP (0.52) | APPKDM4EALDH1A1LMNAL3MBTL1 | |
| Phenylacetylene SCHEMBL28207280 | 0.79 | APP (0.44) | APPKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28486164 | 0.77 | CYP1A2 (0.59) | APPALDH1A1MAPTKCNH2CYP1A2 | |
| SCHEMBL7983223 | 0.74 | APP (0.48) | APPKDM4EALDH1A1LMNAL3MBTL1 | |
| Fluorobenzene SCHEMBL27386177 | 0.74 | CA4 (0.45) | KDM4EALDH1A1LMNAL3MBTL1CYP1A2 | |
| SCHEMBL15348783 | 0.73 | APP (0.42) | APPALDH1A1LMNAL3MBTL1NPC1 | |
| SCHEMBL18867945 | 0.72 | APP (0.67) | APPKDM4EALDH1A1NPC1MAPT | |
| SCHEMBL717468 | 0.72 | APP (0.67) | APPKDM4EALDH1A1NPC1MAPT | |
| SCHEMBL28040646 | 0.71 | APP (0.50) | APPKDM4EALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418623-A | Camptothecin sulfonyl amidine compound and preparation method and application thereof | UNIV LANZHOU | 2016-03-23 | — | — | CN | disclosed |