Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28159616 | 0.97 | APP (0.52) | APPNPC1RAB9AMTORMAPT | |
| Phenylacetylene SCHEMBL28207280 | 0.89 | APP (0.44) | APPNPC1RAB9AMTORMAPT | |
| Fluorobenzene SCHEMBL28040305 | 0.89 | APP (0.44) | APPNPC1RAB9AMTORMAPT | |
| SCHEMBL28486164 | 0.86 | CYP1A2 (0.59) | APPMAPTALDH1A1KCNH2CYP1A2 | |
| SCHEMBL7983223 | 0.83 | APP (0.48) | APPNPC1RAB9AMTORMAPT | |
| SCHEMBL28040646 | 0.80 | APP (0.50) | APPNPC1RAB9AMTORMAPT | |
| SCHEMBL6733118 | 0.79 | CYP1A1 (0.44) | APPKCNH2CYP1A2GRM5CYP1A1 | |
| SCHEMBL9799731 | 0.76 | CA4 (0.35) | APPNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL12332986 | 0.75 | HDAC8 (0.42) | NPC1RAB9AMTORMAPTKDM4E | |
| SCHEMBL1746443 | 0.75 | APP (0.34) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930570-A | Copper complex containing ortho-carborane Schiff base ligand and preparation method and application thereof | 上海应用技术大学 | 2024-11-12 | — | — | CN | claimed |
| EP-3688124-B1 | ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-10-25 | — | — | EP | claimed |
| CN-114716394-B | CdS morphology and S vacancy adjusting C-H activation construction inert chemical bond | 重庆工商大学 | 2023-07-28 | — | — | CN | claimed |
| CN-116396313-A | Alkenyl borate, and preparation method and application thereof | 中山大学 | 2023-07-07 | — | — | CN | claimed |
| CN-111644207-B | Method for catalyzing dehydroboration of alkyne compounds | 苏州大学 | 2023-05-12 | — | — | CN | claimed |
| CN-113105301-B | Method for preparing conjugated diyne compound by using copper complex | 上海应用技术大学 | 2022-10-14 | — | — | CN | claimed |
| CN-111644207-A | Method for catalyzing dehydroboronation reaction of alkyne compound | 苏州大学 | 2020-09-11 | — | — | CN | claimed |
| EP-3223328-B1 | ORGANIC PHOTOVOLTAIC CELL AND MANUFACTURING METHOD THEREOF | KOLON INC (KR) | 2020-07-29 | — | — | EP | claimed |
| CN-110404587-A | A kind of support type cluster catalyst and its preparation and application | UNIV ANHUI | 2019-11-05 | — | — | CN | claimed |
| CN-106986840-B | A kind of synthetic method of polysubstituted 2,3- dihydro-isoxazole class compound | 湖北科技学院 | 2019-08-20 | — | — | CN | claimed |
| US-20040026729-A9 | Memory device | COATUE CORPORATION | 2004-02-12 | — | — | US | claimed |
| US-20030216386-A1 | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 | WEIDNER-WELLS MICHELE A (US) | 2003-11-20 | — | — | US | claimed |
| US-20030178667-A1 | Memory device | CYPRESS SEMICONDUCTOR CORPORATION | 2003-09-25 | — | — | US | claimed |
| US-20030155602-A1 | Memory device | COATUE CORPORATION | 2003-08-21 | — | — | US | claimed |
| EP-0657431-B1 | 4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity | BAYER AG (DE) | 2003-02-19 | — | — | EP | claimed |
| US-20020049213-A1 | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-04-25 | — | — | US | claimed |
| EP-0093010-B1 | ALPHA-HYDROXYETHYLPHOSPHINATES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-06-11 | — | — | EP | claimed |
| EP-0032548-B1 | PROCESS FOR PREPARING ARYL AND HETEROARYL HEXADIENOIC ACIDS | Montedison S.p.A. (IT) | 1983-06-22 | — | — | EP | claimed |
| US-4355168-A | Process for preparing aryl- or heteroarylhexadienoic acids | MONTEDISON S.P.A. (IT) | 1982-10-19 | — | — | US | claimed |
| EP-0032548-A1 | Process for preparing aryl and heteroaryl hexadienoic acids | Montedison S.p.A. (IT) | 1981-07-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216386-A1 | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 | CXCL8, IL18, IL1B | APP 2604/4885NPC1 3541/4885RAB9A 3926/4885 |
| US-20020049213-A1 | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 | CXCL8, IL18, IL1B | APP 2604/4885NPC1 3541/4885RAB9A 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.