Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524129 | 0.76 | SLC22A12 (0.40) | SLC22A12 | |
| SCHEMBL29362515 | 0.76 | SLC22A12 (0.40) | SLC22A12 | |
| SCHEMBL11537975 | 0.69 | RAB9A (0.45) | — | |
| SCHEMBL11537218 | 0.69 | HCAR1 (0.40) | — | |
| SCHEMBL1151405 | 0.67 | MAPK1 (0.41) | HTT | |
| SCHEMBL9895153 | 0.66 | MAPK1 (0.41) | HTT | |
| SCHEMBL21182092 | 0.65 | — | — | |
| SCHEMBL30710586 | 0.65 | RXFP1 (0.48) | HTR6HTTRXFP1 | |
| SCHEMBL29429114 | 0.65 | RXFP1 (0.48) | HTR6HTTRXFP1 | |
| SCHEMBL198796 | 0.65 | RXFP1 (0.48) | HTR6HTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175348-A | Preparation method for lesinurad | BEIJING KANG LISHENG PHARMACEUTICAL TECHNOLOGY DEV CO LTD | 2015-12-23 | — | — | CN | disclosed |