Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28040530 | 0.89 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL28040031 | 0.87 | PPARA (0.40) | PPARGPPARAMAPTALDH1A1KDM4E | |
| SCHEMBL28040727 | 0.82 | SMN1; SMN2 (0.36) | MAPTALDH1A1HSD17B10KMT2AL3MBTL1 | |
| SCHEMBL28040531 | 0.74 | CCR4 (0.32) | PPARGPPARAL3MBTL1 | |
| SCHEMBL28040533 | 0.73 | KMT2A (0.47) | MAPTALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL28040537 | 0.73 | PPARA (0.38) | PPARGPPARAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1395762 | 0.72 | MAPT (0.38) | MAPTTHRBALDH1A1KDM4EKMT2A | |
| SCHEMBL29290738 | 0.71 | SMN1; SMN2 (0.48) | PPARGPPARAMAPTALDH1A1KMT2A | |
| SCHEMBL2090417 | 0.69 | CYP2A6 (0.38) | MAPTALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL28013253 | 0.69 | RIPK1 (0.49) | MAPTALDH1A1KDM4EHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175392-B | A kind of carboxylic acid compound containing thiophene-structure and amide compound containing thiophene-structure and preparation method thereof | 湖南大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-105175392-A | Carboxylic acid compounds containing thiophene structures and amide compounds containing thiophene structures and preparation method for carboxylic acid compounds and amide compounds | UNIV HUNAN | 2015-12-23 | — | — | CN | disclosed |