Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128246 | 0.80 | CA2 (0.50) | CA1CA2CA4CA12CA9 | |
| SCHEMBL1320631 | 0.78 | ALOX15 (0.48) | KDM4EMAPTLMNATSHRNFKB1 | |
| SCHEMBL31464225 | 0.78 | ALOX15 (0.48) | KDM4EMAPTLMNATSHRNFKB1 | |
| SCHEMBL27746371 | 0.75 | SNCA (0.54) | SNCACA1CA2CA4CA6 | |
| SCHEMBL5155604 | 0.75 | CA12 (0.49) | CA1CA2CA4CA6CA12 | |
| SCHEMBL2995205 | 0.74 | TTR (0.54) | SNCACA1CA4CA6CA12 | |
| SCHEMBL30590854 | 0.73 | CA1 (0.61) | SNCACA1CA2CA4CA6 | |
| SCHEMBL3069413 | 0.73 | TMEM97 (0.46) | CA1CA2CA4CA12CA9 | |
| SCHEMBL19193139 | 0.73 | SNCA (0.60) | SNCACA1CA2CA4CA6 | |
| SCHEMBL9618618 | 0.72 | ALOX15 (0.55) | SNCACA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218377-B | A kind of hydroxytyrosol NO donor derivatives and its preparation method and application | 西安交通大学 | 2017-10-27 | — | — | CN | disclosed |
| CN-105218377-A | A kind of Hydroxytyrosol NO donor derivative and its preparation method and application | UNIV XI AN JIAOTONG | 2016-01-06 | — | — | CN | disclosed |